
Epitalon
Source / Derivation:
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Epitalon is a synthetic tetrapeptide derived from the natural pineal peptide epithalamin, originally isolated from the pineal gland. It is associated with regulation of circadian biology, telomere maintenance, and age-related cellular processes.
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Epitalon
Mechanism of Action:
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Epitalon is believed to modulate telomerase activity, support genomic stability, and influence neuroendocrine signaling, including circadian and melatonin pathways. It may also exhibit antioxidant and cytoprotective properties that contribute to improved cellular resilience.​
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Clinical Relevance & Potential Outcomes:
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Preclinical and early clinical studies suggest Epitalon may support healthy aging pathways, circadian rhythm regulation, and markers of cellular function, with potential benefits in sleep regulation, oxidative stress modulation, and overall vitality. It has been explored for its effects on telomere dynamics and age-associated biological markers.​
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Intended Clinical Application:
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Epitalon may be considered for individuals seeking support for sleep–wake regulation, cellular health, or age-related functional decline, particularly where circadian disruption or reduced cellular resilience is a contributing factor.
Formulation & Quality Specifications:
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Delivered as a liquid prefilled pen
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Purity: >98% (HPLC-validated)
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Storage: 2–8 °C (refrigerated)
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Documentation: Full CoA and MSDS available
Concentration:
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Frequency:
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Dosage (pen clicks):
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Duration:
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Notes:
5 mg/ml, total 3 ml, total 15 mg
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Daily​
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10​
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1 month​
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Epitalon is used primarily for anti-aging and telomere support. Short cycles with long breaks are ideal.