Follistatin 344

Source / Derivation:

Follistatin 344 is a naturally occurring glycoprotein predominantly expressed in skeletal muscle, liver, and reproductive tissues. It functions as a potent antagonist of myostatin (GDF-8) and other TGF-β family members, promoting muscle hypertrophy and regeneration.

Follistatin 344

Mechanism of Action:

Follistatin 344 binds to myostatin and activin ligands, preventing their interaction with activin receptors (ActRII/IIb), resulting in increased protein synthesis, satellite cell activation, and myocyte proliferation.

Clinical Relevance & Potential Outcomes:

Follistatin 344 has been investigated for its ability to promote skeletal muscle hypertrophy, counteract muscle-wasting conditions, and enhance tissue regeneration, with potential implications for sarcopenia, cachexia, muscular dystrophies, and post-injury recovery.

Intended Clinical Application:

Follistatin 344 may be considered in patients experiencing muscle atrophy, age-related sarcopenia, post-trauma or post-surgical muscle loss, or other conditions requiring enhanced muscle regeneration.

Formulation & Quality Specifications:

Delivered as a liquid prefilled pen
Purity: >98% (HPLC-validated)
Storage: 2–8 °C (refrigerated)
Documentation: Full CoA and MSDS available

Concentration:

Frequency:

Dosage (pen clicks):

Duration:

Notes:

1 mg/ml, total 3 ml, total 3 mg

Daily

1-2 months

Follistatin has a powerful myostatin-inhibiting effect, so short, intense cycles are recommended with long breaks.

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