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GcMAF

Source / Derivation:

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GcMAF (Gc Protein-Derived Macrophage Activating Factor) is a synthetic peptide derived from the human Gc protein, designed to enhance macrophage activity and immune surveillance. It is widely studied for its role in modulating innate immune responses and supporting cellular defense mechanisms. The peptide has also been explored for its potential in maintaining immune homeostasis in clinical contexts.

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GcMAF

Mechanism of Action:

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GcMAF activates macrophages, enhancing phagocytosis, antigen presentation, and cytokine signaling. This activation promotes more effective immune surveillance and pathogen clearance. Additionally, GcMAF may support the regulation of inflammatory responses, balancing immune activation and preventing excessive inflammation.​

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Clinical Relevance & Potential Outcomes:

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Research suggests GcMAF may support improved innate immunity, enhanced pathogen clearance, and immune system modulation. It is being explored for adjunctive support in immune-compromised patients and in conditions where macrophage activity is diminished. Clinical investigations also indicate potential benefits in enhancing recovery and resilience in stressed or aging immune systems.

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Intended Clinical Application:

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GcMAF may be relevant for patients requiring support for innate immune function, enhanced macrophage activity, or immunomodulatory therapy, particularly in immunocompromised or high-risk populations. It may also be considered in strategies aimed at boosting overall immune readiness.

Formulation & Quality Specifications:

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  • Delivered as a liquid prefilled pen

  • Purity: >98% (HPLC-validated)

  • Storage: 2–8 °C (refrigerated)

  • Documentation: Full CoA and MSDS available

Concentration:

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Frequency:

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Dosage (pen clicks):

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Duration:

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Notes:

12000mg/3ml      ​

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Daily​

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10​

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1 month​

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GcMAF supports immune modulation and is often used in cancer and chronic disease management.

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