
MOTS-c
Source / Derivation:
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MOTS-c is a synthetic mitochondrial-derived peptide designed to regulate metabolism, energy balance, and insulin sensitivity. It is based on a naturally occurring 16-amino acid mitochondrial peptide that plays a role in cellular energy homeostasis. MOTS-c has been investigated for its potential to improve metabolic function and mitochondrial health.
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MOTS-c
Mechanism of Action:
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MOTS-c activates AMP-activated protein kinase (AMPK) pathways, promoting glucose uptake, lipid metabolism, and mitochondrial efficiency. It also modulates cellular energy homeostasis and stress response pathways. Additionally, MOTS-c may enhance exercise capacity, metabolic flexibility, and overall energy balance.
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Clinical Relevance & Potential Outcomes:
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Research indicates MOTS-c may support improved metabolic regulation, enhanced mitochondrial function, and body composition optimization. It has potential applications in metabolic syndrome, insulin resistance, and age-related metabolic decline. Clinical observations suggest benefits in energy management, fat utilization, and cellular resilience.
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Intended Clinical Application:
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MOTS-c may be relevant for patients requiring support for metabolic health, mitochondrial efficiency, or improved energy utilization. It may also be considered in strategies for weight management and metabolic optimization.
Formulation & Quality Specifications:
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Delivered as a liquid prefilled pen
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Purity: >98% (HPLC-validated)
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Storage: 2–8 °C (refrigerated)
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Documentation: Full CoA and MSDS available
Concentration:
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Frequency:
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Dosage (pen clicks):
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Duration:
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Notes:
5 mg/ml, total 3 ml, total 15 mg​
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Daily​
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10​
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1 month​
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MOTS-c mimics the benefits of exercise and enhances mitochondrial function. Cycling it helps avoid desensitization.