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SS-31 (Elamipretide)

Source / Derivation:

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SS-31 is a synthetic mitochondria-targeting peptide designed to protect mitochondrial membranes and improve cellular energy efficiency. It is derived from research into cardiolipin-binding peptides that enhance mitochondrial bioenergetics and reduce oxidative stress.

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SS-31 (Elamipretide)

Mechanism of Action:

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SS-31 selectively binds to cardiolipin in the inner mitochondrial membrane, stabilizing mitochondrial structure, reducing reactive oxygen species (ROS), and enhancing ATP production. It also supports mitochondrial biogenesis and cellular resilience. Additionally, SS-31 may improve tissue recovery and organ function under metabolic stress.

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Clinical Relevance & Potential Outcomes:

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Preclinical and clinical research indicates SS-31 may support improved mitochondrial function, reduced oxidative stress, and enhanced cellular energy metabolism. It has potential applications in cardiovascular health, metabolic disorders, and age-related mitochondrial decline. Clinical observations suggest benefits in tissue resilience, recovery, and overall energy balance.

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Intended Clinical Application:

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SS-31 may be relevant for patients requiring mitochondrial support, oxidative stress reduction, or enhanced cellular energy metabolism. It may also be considered in strategies for organ protection and metabolic optimization.

Formulation & Quality Specifications:

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  • Delivered as a liquid prefilled pen

  • Purity: >98% (HPLC-validated)

  • Storage: 2–8 °C (refrigerated)

  • Documentation: Full CoA and MSDS available

Concentration:

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Frequency:

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Dosage (pen clicks):

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Duration:

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Notes:

10 mg/ml, total 3 ml, total 30 mg​

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Daily​

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10​

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1 month​

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SS-31 is used for mitochondrial health and function. It should be cycled with appropriate breaks.

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